Цитология и иммуноцитохимия В-клеточных неходжкинских лимфом / Д. Ф. Глузман, Л. М. Скляренко, С. В. Коваль и др., 2015. – Семинары по гематопатологии. – Вып. 25.
CYTOLOGY AND IMMUNOCYTOCHEMISTRY OF B-CELL NON-HODGKIN'S LYMPHOMAS /Gluzman D.F., Sklyarenko L.M., Koval S.V., Rodionova N.K., Ivanovskaya T.S., Poludnenko L.Yu., Ukrainskaya N.I., Jalilov A.F. — Kiev: DIA, 2015. — 55 p.
B-cell non-Hodgkin's lymphomas (NHL) represent a heterogeneous group of tumours that arise from developing lymphocytes and depend on numerous highly orchestrated interactions with immune and stromal cells. The current World Health Organization (WHO) classification categorizes NHL into more than 35 distinct entities, primarily on the basis of morphology, immunophenotype, genetic alterations and clinical features.
The most B-cell NHL subtypes are presented as disseminated diseases invol ving lymph nodes, spleen, liver, and often the bone marrow. Tumour cells can also be found in the peripheral blood (leukaemic phase).
Advancement in the understanding of the pathogenesis of lymphomas and the evaluation of prognostic markers is of most importance for selecting the best therapeutic regimens.