November 21-22, 2019 — II International Conference «Tumor and Host: Novel Aspects of Old Problem», dedicated to the 25th anniversary of the Institute membership in the Organisation of European Cancer Institutes

120th tumor host logoOn November 21-22, 2019 the RE Kavetsky IEPOR will host the II International Conference «Tumor and Host: Novel Aspects of Old Problem» in Great Conference Hall of NAS of Ukraine.

tumor host conference 2019


On November 21-22, 2019, the RE Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology of NAS of Ukraine (IEPOR) held the Second International Conference "Tumor and Host: Novel Aspects of Old Problem" in the Great Conference Hall of the National Academy of Sciences of Ukraine. The problem of the tumor-host relationship is a traditional priority for the Institute, the leading institution in the field of cancer research in Ukraine: the concept of the relationship between the tumor and the host has been put forward by the first director of the Institute, Academician R.E. Kavetsky, whose 120th anniversary is celebrated by the Ukrainian scientific community.

The conference was sponsored by the National Academy of Sciences of Ukraine and the Сharitable Organization “Unity Against Cancer” and was dedicated to the 25th anniversary of the Institute's membership in the Organization of European Cancer Institutes (OECI).

The main scientific directions of the conference were devoted to the complex of the most urgent problems of modern experimental and clinical oncology: molecular and cellular pathobiology, metabolic features of the tumor and host, tumor microenvironment, cancer prevention and therapy (new technologies, biotherapy, personalization of treatment).

The conference presented the results of basic and applied research, the purpose of which is future use in clinical practice. Its program included reports on early and differential diagnosis of neoplasms, the identification of aggressive forms of cancer. Much attention was paid to the problems of treatment of cancer patients: features of bio- and chemotherapy, primary and acquired resistance of tumors and, of course, a personalized approach in the choice of schemes and combinations of therapeutic means.

Honorary guests and participants of the event were the representatives of the authorities of the Organization of European Cancer Institutions (OECI). During the conference, 54 scientific reports of scientists from Ukraine, USA, Canada, Italy, Belgium, Sweden, France, Qatar, and Lithuania were presented and discussed.

The conference began from the opening speech with the wishes of fruitful cooperation delivered by the Director of the Institute, Academician of NAS of Ukraine V.F. Chekhun who emphasized that the conference is dedicated to the 25th anniversary of membership of the Institute, the only one from Ukraine, in the OECI, which is a respected European institution dealing with the coordination of cancer research and the cooperation of numerous cancer institutions in Europe. A special celebration of the opening ceremony was given by the choir of the Petro Tchaikovsky National Music Academy of Ukraine performing a number of Ukrainian musical works.



The vice-president of NASU Academician V.G. Koshechko addressed the Conference participants on behalf of the President of NAS of Ukraine Academician B.Ye. Paton, in particular noting: “Academician R.E. Kavetsky, who was the founder of the School of Experimental Oncologists, gave impetus to the formation of new scientific directions of fundamental and applied research, in particular, exploration of the relationship between tumor and host. I am sure that in the course of the conference, scientists and practitioners in the field of oncology will discuss in detail both professional issues and current issues that are of concern to humanity today. The fundamental and applied questions about approaches to diagnostics and treatment of patients with malignant neoplasms will make an important contribution to the development of cancer science and health care." On the behalf of the Verkhovna Rada of Ukraine (Ukrainian Parliament), the guests were greeted by the deputy V.O. Zub

Introductory Lecture by OECI Director Prof. Claudio Lombardo (Brussels, Belgium) was dedicated to the history of the Organization, its mission. He introduced the new OECI initiative, called "European Cancer mission" in the framework of the integrated European program "Horizon". The mission's tasks were discussed in detail, and its ultimate goal was determined - to provide the most optimal affordable treatment for cancer patients in all European countries.

In a key lecture, Prof. Giorgio Stanta, Member of the Board of OECI, Head of the OECI Working Group on Biobanking and Molecular Pathobiology (Trieste, Italy), spoke about the development of precise and personalized medicine in Europe. It is the personalized approach based on determining the individual molecular profile of malignant cells in the coming years that will ensure progress in the treatment of cancer patients.

In his plenary report "MicroRNAs as a key factor in the globalization of the tumor-host relationship", Academician of NAS of Ukraine V.F. Chekhun analyzed the role of these small molecules as extremely important and determining factors in epigenetic regulation, which are decisive in systemic communication between physiological and pathobiological processes, which ultimately determines their role in globalizing the relationship between tumor and host. It was emphasized that studies of the role of microRNAs in tumors and their microenvironment, being now in the spotlight of tumor biology in world science, in Ukraine were initiated exactly in the IEPOR.

Prof. Angelo Paradiso (National Cancer Institute, Bari, Italy) outlined the key issues of biobanking as an important area needed for the further development of translational research and personalized medicine, and acquainted the audience with the basic principles of the organization and functioning of banks of biological materials, mutual exchange of characterized samples between research centers of European countries.

Molecular and biological aspects of the conference topics were highlighted in the lectures and reports by Ya. Shuba (O. Bogomolets Institute of Physiology, NASU, Kyiv, Ukraine), O. Kovalchuk (University of Lethbridge, Alberta, Canada), L. Buchinska (IEPOR NASU, Kyiv, Ukraine) and N. Lukyanova (IEPOR NASU, Kyiv, Ukraine), D. Gluzman (IEPOR NASU, Kyiv, Ukraine), Yu. Persidsky (Temple University, Philadelphia, USA) and other participants.

Within the framework of the conference, on the initiative of OECI representatives, there was held a round table “Ways to implement EU standards for personalized diagnosis and treatment of cancer patients in Ukraine” with the participation of leading oncologists of the country, where issues on improving oncological care for the population of Ukraine, and introduction of European treatment standards for cancer patients were discussed.

In his closing words, the Academician of the NAS of Ukraine VF Chekhun noted that the forum was held in an extremely creative, scientific, friendly atmosphere and highlighted the achievements and perspectives of modern science in the research of the tumor-host relationship.


Program

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Abstracts

Experimental Oncology, 2019, Vol 41, No 3

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2 | 2019-12-05  12815

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